منابع مشابه
Genomics: Evolution of the Genetic Code
The genetic code is not quite universal. The rare variations that we know of reveal selective pressures on the code and on the translation machinery. New data suggest the code changes through ambiguous intermediates and that termination is context dependent.
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15 صفحه اولThe Early Evolution of the Genetic Code
first genetic material may have used a simpler backbone than ribose. One candidate is peptide nucleic acid (PNA), in which the backbone is polymeric N-(2-amino-ethyl)glycine (AEG) and the N-acetic acids of the bases Evolutionary inferences rely on diversity. The source of (N 9 for purines, N 1 for pyrimidines) are linked via amide differences among organisms is accumulated diver-bonds (Figure 1...
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The evolution of the genetic code has been speculated by many authors, but all of them lack determinative proofs. Jukes [4] inferred the evolution from mitochondrial codes, which are different from the universal codes in some respects. He postulated an archetypal code containing 14 amino acids, from which the universal code could evolve by gene duplication followed by mutational changes. This p...
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A fundamental goal of developmental biology is to define the molecular mechanisms that control cell behavior during morphogenesis. A recent study in BMC Biology combines gene expression profiling, bioinformatics and functional analysis to identify genes that shape the Drosophila embryo.
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ژورنال
عنوان ژورنال: Current Biology
سال: 2016
ISSN: 0960-9822
DOI: 10.1016/j.cub.2016.08.005